Agdeppa, ED Kepe, V Liu, J Small, GW Huang, SC Petric, A Satyamurthy, N Barrio, JR 2-Dialkylamino-6-acylmalononitrile substituted naphthalenes (DDNP analogs): novel diagnostic and therapeutic tools in Alzheimer's disease.. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. . 2003; 5(6): 404-17.

G. W. Small, E. Agdeppa, L. M. Ercoli, K. Miller, D. H.S. Silverman, S. Y. Bookheimer, V. Kepe, N. Satyamurthy, S.-C. Huang and J. R. Barrio Genetic Risk and Neuroimaging Measures for Early Detection of Alzheimer?s Disease.. Alzheimer?s disease and Related Disorders: Research Advances 2003; 217-224.

E.D. Agdeppa, V. Kepe, A. Petric, N. Satyamurthy, J. Liu, S-C. Huang, G.W. Small, G. M. Cole and J.R. Barrio In vitro Detection of (S) ? Naproxen and Ibuprofen Binding to Plaques in the Alzheimer?s Brain Using the PET Molecular Imaging Probe [18F] FDDNP.. Neuroscience. 2003; 117: 723-730.

M. Bresjanac, L.M. Smid, T.D. Vovko, A. Petric, J.R. Barrio and M. Popovic Molecular Imaging Probe 2-(1-[6-[(2-Fluoroethyl)(methylamino]-2-naphthyl]ethylidene) malononitrile Labels Prion Plaques In Vitro.. J. Neurosci. 2003; 23: 8029-8033.

J.R. Barrio Molecular Imaging Probes.. PET: Molecular Imaging of Biology 2003; Chapter 5: In Press.

T.Toyokuni, J. C. Walsh, M. Namavari, S. Shinde, J. Moore, J. R. Barrio and N. Satyamurthy Selective and Practical Synthesis of Penciclovir.. Synthetic Communications. 2003; 33: 3897-3905.

T. Toyokuni, J. C. Walsh, A. Dominguez, M. E. Phelps, J. R. Barrio, S. S. Gambhir and N. Satyamurthy Synthesis of a New Heterobifunctional Linker, N-[4-(Aminooxy)butyl]maleimide, for Facile Access to a Thiol-reactive 18F-labeling Agent.. Bioconjugate Chem. 2003; 14: 1253-1259.

I. Penuelas, J. Boan, J.M. Marti-Climent, MA. Barajas, I. Narvaiza, N. Satyamurthy, J.R. Barrio and J. Richter A Full-Automated One Pot Synthesis of [18F]FHBG for Gene Therapy Studies.. Mol. Imaging Biol. 2002; 4: 415-424.

R.E. Yee, S.-C. Huang, D.M. Togasaki, J.W. Langston, N. Satyamurthy and J.R. Barrio Imaging and Therapeutics: The Role of Neuronal Transport in the Central Regional Specificity of L-DOPA Accumulation in Brain.. Mol. Imaging Biol. 2002; 4: 208-218.

Shoghi-Jadid, K Small, GW Agdeppa, ED Kepe, V Ercoli, LM Siddarth, P Read, S Satyamurthy, N Petric, A Huang, SC Barrio, JR Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. . 2002; 10(1): 24-35.

Q. Liang, K. Nguyen, N. Satyamurthy, J.R. Barrio, M.E. Phelps, S.S. Gambhir and H.R. Herschman Monitoring Adenoviral DNA Delivery, Using a Mutant Herpes Simplex Virus Type 1 Thymidine Kinase Gene as a PET Reporter Gene.. Gene Therapy. 2002; 9: 1659-1666.

Q. Liang, J. Gotts, N. Satyamurthy, J.R. Barrio, M.E. Phelps, S.S. Gambhir and H. Herschman Noninvasive, Repetitive, Quantitative Measurement of Gene Expression from a Bicistronic Message by Positron Emission Tomography, Following Gene Transfer with Adenovirus.. Molecular Therapy. 2002; 6: 73-82.

N. Satyamurthy, B. Amarasekera, C. William Alvord, J.R. Barrio and M.E. Phelps Tantalum [18O]Water Target for the Production of [18F]Fluoride with High Reactivity for the Preparation of 2-Deoxy-2-[18F]Fluoro-D-Glucose.. Mol. Imaging Biol.. 2002; 4: 65-70.

M. Iyer, J.R. Barrio, M. Namavari, E. Bauer, N. Satyamurthy, L.A. Green, K. Nguyen, S.R. Cherry, T. Toyokuni, M.E. Phelps, H.R. Herschman and S.S. Gambhir 8-[18F]-Fluoropenciclovir: An Improved Reporter Probe for Imaging HSV1-tk Reporter Gene Expression In Vivo Using Positron Emission Tomography.. J. Nucl. Med.. 2001; 42: 96-105.

E.D. Agdeppa, V. Kepe, J. Liu, S. Flores-Torres, N. Satyamurthy, A. Petric, G.M. Cole, G.W. Small, S.-C. Huang and J.R. Barrio Binding Characteristics of Radiofluorinated 6-Dialkylamino-2-Napthylethylidene Derivatives as PET Imaging Probes of b-amyloid Plaques in Alzheimer?s Disease.. J. Neurosci.. 2001; 21: 181-185.

R.E. Yee, D.W. Cheng, S.-C. Huang, M. Namavari, N. Satyamurthy and J.R. Barrio Blood-Brain Barrier and Neuronal Membrane Transport of 6-[18F]Fluoro-L-DOPA.. Biochem. Pharmacol.. 2001; 62: 1409-1415.

S. Yaghoubi, J.R. Barrio, M. Dahlbom, M. Iyer, M. Namavari, N. Satyamurthy, R. Goldman, H.R. Herschman, M.E. Phelps and S.S. Gambhir Human Pharmacokinetic and Dosimetry Studies of [18F]FHBG, A Reporter Probe for Imaging Herpes Simplex Virus Type I Thymidine Kinase (HSV1-tk) Reporter Gene Expression.. J. Nucl. Med.. 2001; 42: 1225-1234.

P. Ray, E. Bauer, M. Iyer, J.R. Barrio, N. Satyamurthy, M.E. Phelps, H.R. Herschman and S.S. Gambhir Monitoring Gene Therapy with Reporter Gene Imaging.. Semin. Nucl. Med. 2001; 31: 312-320.

Q. Liang,. N. Satyamurthy, J.R. Barrio, T. Toyokuni, M.E. Phelps, S.S. Gambhir and H.R. Herschman Non-invasive, Quantitative Imaging in Living Animals of a Mutant Dopamine D2 Receptor Reporter Gene in which Ligand Binding is Uncoupled from Signal Transduction.. Gene Therapy. 2001; 8: 1490-1498.

D.B. Stout, S.-C. Huang, M. Namavari, R.E. Yee, N. Satyamurthy and J.R. Barrio Distribution Volume of 3-O-Methyl-6-[F-18]FDOPA in Rat Brain.. J. Cereb. Blood Flow Metab.. 2000; 20: 1717-1724.

S.S. Gambhir, H.R. Herschman, S.R. Cherry, J.R. Barrio, N. Satyamurthy, T. Toyokuni, M.E. Phelps, S.M. Larson, J. Balatoni, R. Finn, J. Tjuvajev, and R. Blasberg Imaging Transgene Expression with Radionuclide Imaging Technology.. Neoplasia. 2000; 2: 118-138.

D.C. MacLaren, T. Toyokuni, S.R. Cherry, J.R. Barrio, M.E. Phelps, H.R. Herschman and S.S. Gambhir PET Imaging of Transgene Expression.. Biol. Psychiatry 2000; 48: 337-348.

S. Sun, A.J. Annala, J.R. Barrio, T. Toyokuni, N. Satyamurthy, M. Namavari, S.R. Cherry, M.E. Phelps, H.R. Herschman and S.S. Gambhir Quantitation of Target Gene Expression by Imaging Reporter Gene Expression in Living Animals.. Nature Medicine. 2000; 6: 933-937.

K. Shoghi-Jadid, S.-C. Huang, D.B. Stout, R.E. Yee, E.L. Yeh, K.F. Farahani, N. Satyamurthy and J.R. Barrio Striatal Kinetic Modeling of FDOPA with a Cerebellar-derived Constraint on the Distribution Volume of 3OMFD: A Positron Emission Tomography (PET) Investigation Using Non-Human Primates.. J. Cereb. Blood Flow Metab.. 2000; 20: 1134-1148.

M. Namavari, J.R. Barrio, S.S. Gambhir, S.R. Cherry, H.R. Herschman, M.E. Phelps and N. Satyamurthy Synthesis of 8-[18F]Fluoroguanine Derivatives: In-vivo Probes for Imaging Gene Expression with PET.. Nucl. Med. Biol. 2000; 27: 157-162.

Maclean, D Zhu, J Chen, M Hale, R Satymurthy, N Barrio, JR Safety-catch linker strategies for the production of radiopharmaceuticals labeled with positron-emitting isotopes.. Journal of the American Chemical Society. . 2003; 125(34): 10168-9.

Inubushi, M Wu, JC Gambhir, SS Sundaresan, G Satyamurthy, N Namavari, M Yee, S Barrio, JR Stout, D Chatziioannou, AF Wu, L Schelbert, HR Positron-emission tomography reporter gene expression imaging in rat myocardium.. Circulation. . 2003; 107(2): 326-32.

Small, GW Agdeppa, ED Kepe, V Satyamurthy, N Huang, SC Barrio, JR In vivo brain imaging of tangle burden in humans.. Journal of molecular neuroscience : MN. . 2002; 19(3): 323-7.

Green, LA Yap, CS Nguyen, K Barrio, JR Namavari, M Satyamurthy, N Phelps, ME Sandgren, EP Herschman, HR Gambhir, SS Indirect monitoring of endogenous gene expression by positron emission tomography (PET) imaging of reporter gene expression in transgenic mice.. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. . 2002; 4(1): 71-81.

Sun, X Annala, AJ Yaghoubi, SS Barrio, JR Nguyen, KN Toyokuni, T Satyamurthy, N Namavari, M Phelps, ME Herschman, HR Gambhir, SS Quantitative imaging of gene induction in living animals.. Gene therapy. . 2001; 8(20): 1572-9.

Yee, RE Irwin, I Milonas, C Stout, DB Huang, SC Shoghi-Jadid, K Satyamurthy, N Delanney, LE Togasaki, DM Farahani, KF Delfani, K Janson, AM Phelps, ME Langston, JW Barrio, JR Novel observations with FDOPA-PET imaging after early nigrostriatal damage.. Movement disorders : official journal of the Movement Disorder Society. . 2001; 16(5): 838-48.

Yaghoubi, SS Wu, L Liang, Q Toyokuni, T Barrio, JR Namavari, M Satyamurthy, N Phelps, ME Herschman, HR Gambhir, SS Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors.. Gene therapy. . 2001; 8(14): 1072-80.

Rasgon, NL Small, GW Siddarth, P Miller, K Ercoli, LM Bookheimer, SY Lavretsky, H Huang, SC Barrio, JR Phelps, ME Estrogen use and brain metabolic change in older adults. A preliminary report.. Psychiatry research. . 2001; 107(1): 11-8.

Small, GW Ercoli, LM Silverman, DH Huang, SC Komo, S Bookheimer, SY Lavretsky, H Miller, K Siddarth, P Rasgon, NL Mazziotta, JC Saxena, S Wu, HM Mega, MS Cummings, JL Saunders, AM Pericak-Vance, MA Roses, AD Barrio, JR Phelps, ME Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease.. Proceedings of the National Academy of Sciences of the United States of America. . 2000; 97(11): 6037-42.

Herschman, HR MacLaren, DC Iyer, M Namavari, M Bobinski, K Green, LA Wu, L Berk, AJ Toyokuni, T Barrio, JR Cherry, SR Phelps, ME Sandgren, EP Gambhir, SS Seeing is believing: non-invasive, quantitative and repetitive imaging of reporter gene expression in living animals, using positron emission tomography.. Journal of neuroscience research. . 2000; 59(6): 699-705.

Gambhir, SS Bauer, E Black, ME Liang, Q Kokoris, MS Barrio, JR Iyer, M Namavari, M Phelps, ME Herschman, HR A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography.. Proceedings of the National Academy of Sciences of the United States of America. . 2000; 97(6): 2785-90.

Yee, RE Huang, SC Stout, DB Irwin, I Shoghi-Jadid, K Togaski, DM DeLanney, LE Langston, JW Satyamurthy, N Farahani, KF Phelps, ME Barrio, JR Nigrostriatal reduction of aromatic L-amino acid decarboxylase activity in MPTP-treated squirrel monkeys: in vivo and in vitro investigations.. Journal of neurochemistry. . 2000; 74(3): 1147-57.

Satyamurthy, N Phelps, ME Barrio, JR Electronic Generators for the Production of Positron-Emitter Labeled Radiopharmaceuticals. Where Would PET Be Without Them?. Clinical Positron Imaging. 1999; 2(5): 233-253.