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Post-Doctoral Training


Clinical and Fundamental Immunology Training Grant

Director: Andrew Saxon, MD

The objectives of this training program are to develop knowledgeable investigators who can conduct independent research and function creatively at one or more frontiers of basic and/or clinical immunology. Ultimately, they should be able to assist and instruct other young colleagues in their career development. At UCLA, strong research programs and training resources have been developed in:
  1. Molecular immunology, especially concerned with differentiation at the transcription and post-transcription level, and with antigens at the cell surface.
  2. Immune response regulation and humoral and cellular interrelationships.
  3. Immune competence and amplification mechanisms.
  4. Immunopathogenesis in disease.
  5. Immune-based therapies and vaccines.
  6. Biology of cancer and immunotherapy of cancer. gene therapy.
Major emphasis goes way beyond the traditional areas of clinical immunology (allergy, autoimmunity and immunodeficiency with major immunology programs existing in , organ and bone marrow transplantation, aging,, oncology, histopathology, and immunogenetics. The faculty preceptors (14 Ph.D.; 11 M.D.; 3 M.D./Ph.D.) have their principal appointment in four basic science departments (Biology, Microbiology and Immunology, Microbiology and Molecular Genetics, and Pathology) and the three major clinical departments, Medicine, Pediatrics, and Surgery. In addition to traditional interdepartmental activities, training is conducted in conjunction with the Mac Donald Howard Hughes Medical Institute, the Molecular Biology Institute, the UCLA AIDS Institute and the Jonsson Comprehensive Cancer Center.

The UCLA Basic and Clinical Immunology Training Program is the sole campus program offering comprehensive training in Basic Clinical Immunology at the graduate and postgraduate levels. All of the faculty are engaged directly in research in the field of immunobiology or closely related fundamental research. Postdoctoral trainees are evaluated by an advisory committee with emphasis being given to candidates who have been accepted into the UCLA STAR program by the Interdepartmental STAR Committee. Trainees participate in cohesive UCLA Immunology Programs which emphasize collaboration and cooperation in research and training. The Program supports campus seminars on basic or clinical biology of cancer and immunology topics and informs trainees of campus immunology- and cancer-related activities.

The proposed training program contains several major elements:
  1. Research experience in a stimulating environment with an established scientist.
  2. Intensive instruction in immunological sciences via lectures, seminar courses, laboratory workshops, symposia, and affinity groups in research
  3. Synthesis and extrapolation (putting-it-together) by participation in local research seminars, presentations at the Trainee Retreat(s) and at regional, national (and international) meetings, and preparation of manuscripts for publication.
All trainees and preceptors participate in reading, interactive workshops and courses on bioethics.
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